教师基本信息
职称:教授/博士生导师
办公电话:021-51630534
电子邮箱: fangchang@fudan.edu.cn
办公地址:幸福宝导航app入口E401-6室
个人简介
女,1980年出生于河北保定。2009年获得中国农业大学植物学博士学位;2009年-今,幸福宝导航app入口,讲师、副教授、教授/博导。期间,2006-2007年美国加州大学河滨分校植物系访问学者;2013年澳洲昆士兰科技大学教育系访问学者。国家优秀青年科学基金获得者(2018)。上海市优秀党务工作者(2019),国家及上海市高校“双带头人”教师党支部书记工作室负责人。中国植物生理与分子生物学学会女科学家分会委员,上海生化与分子生物学学会理事。主要关注植物雄性育性的调控机制和环境响应,研究成果发表于Plant Cell,Mol. Plant, Plant Phys., Curr. Opin. Plant Biol.等国际植物学前沿期刊。
主要研究方向
课题组综合利用分子遗传、细胞生物学、基因组学、蛋白质组学、生物信息学、以及合成生物学方法,系统研究(1)花药早期极性建立和形态建成;(2)生殖细胞的发生和发育;(3)环境胁迫条件下的育性维持机制。
获奖情况
国家优秀青年科学基金获得者(2018)
上海市“优秀党务工作者”(2019)
复旦大学“三八红旗手”(2019)
复旦大学“卓学计划”(2015)
复旦大学“十佳辅导员”(2013)
代表性成果(仅列第一或通讯作者)
Fu Y., Li M, Zhang S, Yang Q, Zhu E, You C, Qi J, Ma H*, Chang F* (2020) Analyses of functional conservation and divergence reveals requirement of bHLH010/089/091 for pollen development at elevated temperature in Arabidopsis. JGG, https://doi.org/10.1016/j.jgg. 2020.09.001.【封面文章】
Lu J#, Fu Y#, Li M, Wang S, Wang J, Yang J, Ye J, Zhang X, Ma H*, Chang F* (2020) Global Quantitative Proteomics Studies Revealed Tissue-Preferential Expression and Phosphorylation of Regulatory Proteins in Arabidopsis. Int. J. Mol. Sci. 21, 6116; doi:10.3390/ijms21176116.
Wang S., Lu J., Song X-F., Ren S-C., You C., Xu J., Liu C-M., Ma H., Chang F.* (2017) Cytological and Transcriptomic Evidence Reveal Important Roles of CLE19 in Pollen Exine Formation.Plant Physiol. 175:1186-1202.
Chang F., Cui J., Wang L., Ma H.* (2017) The BIF Domain is Structurally and Functionally Distinct from Other Types of ACT-like Domains.Plant Cell, 29:1803-1805.
Zhang S-S., Yang H., Ding L., Song Z-T., Ma H., Chang F. *, Liu J-X. * (2017) Tissue-Specific Transcriptomics Reveals an Important Role of the Unfolded Protein Response in Maintaining Fertility upon Heat Stress in Arabidopsis.Plant Cell, 29:1007-1023.
Cui J., You C., Zhu E., Huang Q., Ma H. *, Chang F*. (2016) Feedback Regulation of DYT1 by Interactions with Downstream bHLH Factors Promotes DYT1 Nuclear Localization and Anther Development.Plant Cell, 28:1078-1093.【highlighted paper】
Zhu E. #, You C. #, Wang S., Cui J., Niu B., Wang Y., Qi J., Ma H. *, Chang F.* (2015) The DYT1-interacting proteins bHLH010, bHLH089, and bHLH091 are redundantly required for Arabidopsis anther development and transcriptome.Plant J. 83:976-990.
Yang H.#, Chang F.#,*, You C., Cui J., Zhu G., L., Zheng Y., Qi J. *, Ma H.* (2015) Whole genome DNA methylation patterns and complex associations with gene structure and expression during flower development in Arabidopsis.Plant J. 81: 268-281.
Chang F., Zhang Z., Jin Y., Ma, H*. Cell biological analyses of anther morphogenesis and pollen viability in Arabidopsis and rice. Methods Mol. Biol. 2014,1110:203-16.
Chang F.#, Gu Y.#, Ma H., Yang Z*. AtPRK2 promotes ROP1 activation via phosphorylation of RopGEFs to control polarized pollen tube growth. Mol. Plant2013,6:1187-1201.
Chang F. #, Wang Y. #, Wang S., Ma H*. Molecular control of microsporogenesis in Arabidopsis. Curr. Opin. Plant Biol.2011,14:66-73.